Florinef Uses And Side Effects

FLORINEF (FLUDROCORTISONE)

Florinef Information

Florinef belongs to the type of drugs called steroids. The body naturally creates steroids that are similar to Florinef.

Florinef Acetate (Fludrocortisone Acetate Tablets USP) contains fludrocortisone acetate, a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity; it is used only for its mineralocorticoid effects. The chemical name for fludrocortisone acetate is 9-fluoro- 11ß,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate.

Florinef Uses

Sometimes the body experiences conditions in which they cannot or does not produce a sufficient amount of steroids, like Addison’s disease, and salt-losing adrenogenital syndrome. Florinef functions in the body by treating the said conditions. Florinef could also be used in other purposes not mentioned here.Florinef Acetate is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome.

 It is used along with other medications to treat low glucocorticoid levels caused by disease of the adrenal gland (e.g., Addison's disease, adrenocortical insufficiency, salt-losing adrenogenital syndrome). Glucocorticoids are needed in many ways for the body to function well. They are important for salt and water balance and keeping blood pressure normal. They are also needed to break down carbohydrates in your diet.

Florinef Warnings

Florinef lessens the body’s ability to fight infection so avoid taking this medication if you have serious bacterial, viral, or fungal infection. Talk to your doctor first before taking this medication if you have kidney disease, diabetes mellitus, Myasthenia gravis, Ulcerative Colitis, hypothyroidism, high blood pressure or heart disease, liver disease, tuberculosis, psychiatric conditions, stomach ulcers, osteoporosis, or any other medical conditions. Your doctor might not allow you to take Florinef, adjust your dose or require you a specials monitoring during the treatment. This medication belongs to the FDA pregnancy category C. It is unknown whether this medication could cause harm to an unborn baby. Talk to your doctor first before taking Florinef if you are pregnant. Talk to your doctor first before taking this medication if you are breast-feeding an infant because this passes in breast milk.

Florinef Intake Guidelines

Follow the exact direction given to you by your doctor in taking Florinef. In case you did not understand the instructions, do not hesitate to ask your doctor, pharmacist or nurse to explain them to you. It is advisable to take every dose of this medication with a full glass of water. To reduce stomach upset, you may take this medication with milk or food. If possible, take this medication at the same time every day. If you are taking this medication for several weeks, talk to your doctor first before you stop taking this medication.

Florinef Dosage

You may obtain the dose of Florinef from your doctor. Follow the exact dose given to you by your doctor.

The usual dose is 0.1 mg of Florinef Acetate daily, although dosage ranging from 0.1 mg three times a week to 0.2 mg daily has been employed. In the event transient hypertension develops as a consequence of therapy, the dose should be reduced to 0.05 mg daily. Florinef Acetate is preferably administered in conjunction with cortisone (10 mg to 37.5 mg daily in divided doses) or hydrocortisone (10 mg to 30 mg daily in divided doses).

Florinef Overdose

Some of the signs of overdose with Florinef are weight gain, swelling or water retention, high blood pressure and low levels of potassium in the blood. Look for emergency medical attention if you suspect an overdose or experience any of the said signs of overdose. Taking a large dose of this medication, even once is unlikely to cause symptoms or death.
Florinef Missed Dose
In case you miss a dose of this medication, take the missed dose as soon as you recall but if it is almost time for the next dose, skip the missed dose and take the next dose that was regularly scheduled. Avoid taking a double dose of this medication.

Florinef Side Effects

Some of the serious side effects of Florinef are allergic reactions such as closing of your throat, difficulty in breathing, swelling of the lips and hives; severe or continuing headache; sudden weight gain; dizziness or fainting; swelling of the feet or ankles; increased blood pressure; and difficulty in breathing. If you experience any of the said serious side effects, stop taking Florinef and look for emergency medical attention. Some other side effects of this medication are muscle weakness or joint pain, glaucoma, cataracts, thinning of your skin, nausea or stomach upset, fatigue, increased hunger or thirst, problems with diabetes control, osteoporosis, round face, and changes in behavior. If you experience any of the said side effects, inform your doctor about it. Some side effects that are not mentioned here may also occur. Talk to your doctor if you experience any unusual or bothersome side effects.

Less Side Effects:

• Acne, pimples

• bruising, large, flat, blue or purplish patches in the skin

• change in color of skin or nails

• increased sweating

• loss of muscle mass

• menstrual changes

• muscle weakness

• reddish purple lines on arms, face, legs, trunk, or groin

• sleeplessness, trouble sleeping, unable to sleep

• small, red, or purple spots on skin

• swelling of abdominal or stomach area, full or bloated feeling or pressure in the stomach

• thin, fragile skin

• unusual increase in hair growth

Florinef Drug Reactions

Talk to your doctor first before taking Florinef if you are taking other medicines like barbiturate like amobarbital, secobarbital, pentobarbital or Phenobarbital; birth control pills like Ortho Novum, Ovral, Lo-Ovral, Triphasil, Levlen , Tri-Levlen, Alesse, Desogen, and others; diuretic like furosemide, ethacrynic acid, bumetanide, or torsemide; estrogen like Premarin, Ogen, Estratest, Estraderm, Vivelle, Climara, Fempatch, and others; insulin or an oral diabetes medicine like chlorpropamide or glyburide; anabolic steroid like oxymetholone, nandrolone, and others phenytoin or ethotoin; rifampin; digoxin; amphotericin B; warfarin; and aspirin. Your doctor might adjust your dose or require you a special monitoring during the treatment with Florinef if you are taking the said medicines. Other drugs not mentioned here may also affect Florinef. Talk to your doctor first before taking other medicines or over-the-counter medicines.

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In some countries FLORINEF may also be known as: Fludrocortisone, FLOVENT

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